Heart pacemaker tweak aimed at easing chest pain and fatigue – but study stopped early

NCT ID NCT06775886

Terminated Symptom relief Sponsor: Montefiore Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether a personalized pacing algorithm (myPACE+) could improve quality of life and exercise capacity in people with non-obstructive hypertrophic cardiomyopathy who already have an implantable defibrillator. Only one person was enrolled before the trial was terminated, so no meaningful results were obtained. The idea was to see if tailored pacing could reduce symptoms like shortness of breath and fatigue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: myPACE+ algorithm (personalized accelerated pacing via implanted ICD)
What this could lead to: If it worked, this could offer a non-drug way to ease symptoms and improve daily life for people with this type of heart condition.
What could go wrong: The trial was terminated after enrolling only 1 participant, so no reliable conclusions can be drawn. The approach is experimental and unproven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiomyopathy hypertrophic cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTROPHIC CARDIOMYOPATHY NON-OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY

Contacts and locations

Locations

Montefiore Medical Center

The Bronx, New York, 10467, United States

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