Custom-Made cancer vaccines enter human testing

NCT ID NCT05741242

First seen Jan 16, 2026 · Last updated Jun 20, 2026 · Updated 19 times

Summary

This trial tests a personalized vaccine made from unique proteins in a patient's tumor. The goal is to train the immune system to recognize and attack cancer cells. It is open to people with solid tumors that have spread or are locally advanced. The study will check if the vaccine is safe and can help stop the cancer from growing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Anna Gattani MD PC

    New York, New York, 10028, United States

  • Mount Sinai Comprehensive Cancer Center

    Miami Beach, Florida, 33140, United States

  • Precision NextGen Oncology & Research Center

    Beverly Hills, California, 90212, United States

  • Quest Clinical Research

    San Francisco, California, 94115, United States

  • St. Louis Cancer Care

    Bridgeton, Missouri, 63044, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

personalized synthetic long peptide vaccine

What this could lead to

If this works, it could point toward a new way to train the immune system to fight cancer, potentially slowing tumor growth or preventing recurrence.

What could go wrong

This is an early-phase trial (1b/2) with a small number of participants, so results may not apply broadly. The vaccine is personalized, making it complex and costly, and it may not work for all tumor types.

Conditions

The condition(s) this trial relates to.

cancer glioblastoma neoplasm pancreatic adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.