Gum disease study seeks clues in saliva and plaque

NCT ID NCT04831060

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to better understand periodontitis and peri-implantitis by analyzing biological samples like plaque, saliva, and gum fluid from 219 participants. Researchers will compare samples from people with severe gum disease to those with healthy gums. The goal is to identify molecular markers that could lead to improved prevention, screening, and treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could identify new biomarkers or drug targets for better diagnosis and treatment of periodontitis and peri-implantitis.
What could go wrong
This is an observational study focused on understanding disease mechanisms, not testing a new treatment. It may not directly lead to new therapies.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Inflammation Peri-Implantitis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dentistry department- Rothschild hospital

    RECRUITING

    Paris, 75012, France

  • Service d'odontologie, hôpital Charles Foix

    RECRUITING

    Ivry-sur-Seine, 94200, France

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