Gum disease study seeks clues in saliva and plaque
NCT ID NCT04831060
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aims to better understand periodontitis and peri-implantitis by analyzing biological samples like plaque, saliva, and gum fluid from 219 participants. Researchers will compare samples from people with severe gum disease to those with healthy gums. The goal is to identify molecular markers that could lead to improved prevention, screening, and treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify new biomarkers or drug targets for better diagnosis and treatment of periodontitis and peri-implantitis.
- What could go wrong
- This is an observational study focused on understanding disease mechanisms, not testing a new treatment. It may not directly lead to new therapies.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dentistry department- Rothschild hospital
RECRUITINGParis, 75012, France
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Service d'odontologie, hôpital Charles Foix
RECRUITINGIvry-sur-Seine, 94200, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Blood-Derived clot may regrow bone in gum disease
- Can gum disease around implants diminish quality of life?
- Can special alloy rings keep dental implants cleaner?
- Can gum disease be stopped by targeting these genes?
- Could saliva hold the key to understanding gum disease?