Vein bypass offers hope for leg amputation patients
NCT ID NCT03807661
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new procedure called percutaneous deep vein arterialization for people with critical limb ischemia, a severe form of leg artery disease. The procedure uses a device to create a bypass using a vein, aiming to improve blood flow and prevent amputation. The study included 28 people who had no other treatment options and measured how many survived without losing a limb.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LimFlow System (a device to create a vein bypass)
What this could lead to
If it works, this could offer a new way to save limbs and improve blood flow in people with severe leg artery disease who have no other options.
What could go wrong
This was a small, early study with only 28 people, so results may not apply to everyone. The procedure carries risks like infection, bleeding, or the bypass failing over time.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Glenfield Hospital
Leicester, LE3 9QP, United Kingdom
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Guy's and St Thomas' NHS Foundation Trust
London, SE1 9RT, United Kingdom
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Manchester University NHS Foundation Trust
Manchester, M13 9WL, United Kingdom
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North Bristol NHS Trust
Bristol, BS10 5NB, United Kingdom
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Royal Liverpool and Broadgreen University Hospitals NHS Trust
Liverpool, L7 8XP, United Kingdom
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St George's University Hospitals NHS Foundation Trust
London, SW17 0RE, United Kingdom