New drug combo aims to shrink Hard-to-Treat sarcomas
NCT ID NCT05711615
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 29 times
Summary
This early-phase trial tests whether combining two drugs—peposertib and a low-dose form of the chemotherapy doxorubicin—is safe and effective for people with advanced sarcomas that have spread or can't be removed by surgery. About 30 adults with specific sarcoma types will receive the combination to find the best dose and see if it can shrink tumors or slow the disease. The study is currently recruiting.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
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Johns Hopkins University/Sidney Kimmel Cancer Center
RECRUITINGBaltimore, Maryland, 21287, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Los Angeles General Medical Center
RECRUITINGLos Angeles, California, 90033, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Cancer Institute Developmental Therapeutics Clinic
RECRUITINGBethesda, Maryland, 20892, United States
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Siteman Cancer Center-South County
RECRUITINGSt Louis, Missouri, 63129, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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UC Comprehensive Cancer Center at Silver Cross
RECRUITINGNew Lenox, Illinois, 60451, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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UCHealth University of Colorado Hospital
RECRUITINGAurora, Colorado, 80045, United States
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USC / Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
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Contact Phone: •••-•••-••••
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University of Chicago Comprehensive Cancer Center
SUSPENDEDChicago, Illinois, 60637, United States
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University of Chicago Medicine-Orland Park
SUSPENDEDOrland Park, Illinois, 60462, United States
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University of Miami Miller School of Medicine-Sylvester Cancer Center
RECRUITINGMiami, Florida, 33136, United States
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Contact Phone: •••-•••-••••
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University of Michigan Rogel Cancer Center
SUSPENDEDAnn Arbor, Michigan, 48109, United States
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University of Pittsburgh Cancer Institute (UPCI)
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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Contact Phone: •••-•••-••••
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University of Virginia Cancer Center
RECRUITINGCharlottesville, Virginia, 22908, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.