New vaccine combo aims to fight deadly childhood brain cancers

NCT ID NCT06639607

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 24 times

Summary

This early-stage trial tests a combination of a vaccine targeting a common virus (CMV) and an immunotherapy drug (nivolumab) in children and young adults with aggressive brain tumors like diffuse midline glioma and medulloblastoma. The goal is to see if this approach is safe and can boost the immune system to fight the cancer. About 68 participants will be enrolled across multiple sites.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

Conditions

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