Common drug may shield kidneys from chemo harm
NCT ID NCT05640817
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether pentoxifylline, a drug used for blood flow problems, can protect the kidneys from damage caused by cisplatin chemotherapy in head and neck cancer patients. 90 adults receiving cisplatin for the first time took part. Researchers measured kidney injury using standard tests and a specific marker called KIM-1.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pentoxifylline
What this could lead to
If it works, this could offer a simple way to reduce kidney damage from cisplatin chemotherapy, helping patients complete their cancer treatment with fewer side effects.
What could go wrong
This is a small, completed study without a phase designation, so results may not be definitive. Pentoxifylline may not provide meaningful protection for all patients, and its benefits need confirmation in larger trials.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEAD AND NECK SQUAMOUS CELL CARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Tanta Unuversity
Tanta, 34518, Egypt