Ultrasound boosts cancer drug in tiny trial
NCT ID NCT07501650
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tests whether using ultrasound and microbubbles can help the immunotherapy drug pembrolizumab (Keytruda) work better in people with head and neck cancer that has come back or spread. Only 6 participants will receive three rounds of treatment. The main goal is to see if the approach is feasible, not yet to measure how well it fights cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pembrolizumab (Keytruda) and Definity (microbubbles)
What this could lead to
If it works, this could point toward a way to make immunotherapy more effective for head and neck cancer by using ultrasound to help the drug reach tumors.
What could go wrong
This is a very small, early feasibility trial with only 6 people. It is designed to see if the procedure is possible, not to prove it works. There may be side effects from the drug or ultrasound.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••