New combo tackles brain tumors in Tough-to-Treat cancers

NCT ID NCT04955743

First seen Dec 29, 2025 · Last updated May 02, 2026 · Updated 24 times

Summary

This study tested a combination of two drugs, pembrolizumab and lenvatinib, in 18 adults with melanoma or kidney cancer that had spread to the brain. All participants had already been treated with similar immunotherapy drugs. The goal was to see if the combination could shrink brain tumors. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Yale University

    New Haven, Connecticut, 06517-3534, United States

Conditions

Explore the condition pages connected to this study.