New hope for bile duct cancer? keytruda and lenvima combo tested
NCT ID NCT04550624
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tested a combination of two drugs, pembrolizumab (Keytruda) and lenvatinib (Lenvima), in 27 people with advanced biliary tract cancer that had worsened after standard treatment. The goal was to see if the combination could shrink tumors. The study is now complete.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pembrolizumab (Keytruda) and lenvatinib (Lenvima)
What this could lead to
If successful, this combination could offer a new treatment option for people with advanced biliary tract cancer who have run out of standard therapies.
What could go wrong
This is a small, early-phase study with only 27 participants, so results may not apply to everyone. The combination may cause significant side effects and may not improve survival.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Shanghai Jiahui International Hospital
Shanghai, Shanghai Municipality, 200233, China
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Shanghai Zhongshan Hospital
Shanghai, Shanghai Municipality, 200233, China