New cocktail targets Hard-to-Treat brain cancer
NCT ID NCT04421560
First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 22 times
Summary
This study tests a combination of three drugs (pembrolizumab, ibrutinib, and rituximab) in about 37 people whose primary central nervous system lymphoma has come back or not responded to prior treatment. The goal is to see if the combo can stop the cancer from growing for at least 6 months. Participants will receive the drugs intravenously or by mouth, and researchers will monitor side effects and tumor response.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-••••
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Columbia University Medical Center
WITHDRAWNNew York, New York, 10032, United States
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact
Conditions
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