Ovarian cancer vaccine combo shows promise in early trial

NCT ID NCT03029403

First seen Nov 01, 2025 · Last updated May 18, 2026 · Updated 31 times

Summary

This phase 2 study tested whether combining an experimental vaccine (DPX-Survivac) with an immunotherapy drug (pembrolizumab) and low-dose chemotherapy can shrink tumors in people with advanced ovarian, fallopian tube, or peritoneal cancer. The vaccine trains the immune system to attack cancer cells, while pembrolizumab helps the immune system stay active. The study enrolled 47 participants whose cancer had returned after prior treatment. The main goal was to see how many patients responded to the treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.