Could a white blood cell booster help shrink breast tumors before surgery?

NCT ID NCT03571633

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether adding pegfilgrastim (a drug that increases white blood cells) to standard chemotherapy and trastuzumab can help the immune system better attack HER2-positive breast cancer before surgery. About 90 women with early-stage, operable breast cancer will take part. The main goal is to see if more tumors completely disappear after treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHRU Besançon

    Besançon, 25000, France

  • Centre Hospitalier Annecy Genevois

    Pringy, France

  • Centre Hospitalier Universitaire de Saint Etienne

    Saint-Etienne, France

  • Centre Leon Berard

    Lyon, France

  • Centre de Lutte contre le Cancer Jean Perrin

    Clermont-Ferrand, 63000, France

  • Clinique Charcot

    Sainte-Foy-lès-Lyon, France

  • Groupe Hospitalier Mutualiste de Grenoble

    Grenoble, 38000, France

  • Hopital Prive Jean Mermoz

    Lyon, France

  • Institut Sainte Catherine

    Avignon, France