Does losing your appendix change how gut bugs bounce back after colonoscopy?

NCT ID NCT07478029

Recruiting now Knowledge-focused Sponsor: Huaping Xie Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how a common bowel-cleansing drink (PEG) used before colonoscopy changes the gut bacteria in people who have had their appendix removed. Researchers will compare these changes to those in people with an intact appendix. The goal is to understand if the appendix plays a role in helping gut bacteria recover after colonoscopy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Polyethylene glycol (PEG) laxatives
What this could lead to: If successful, this study could reveal whether the appendix helps restore gut bacteria after colonoscopy, and whether its removal affects long-term gut health.
What could go wrong: This is a very small, early-stage observational study with only 10 participants. It does not test a treatment, so results may not lead to direct health changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

appendicitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APPENDICITIS APPENDICITIS ACUTE

Contacts and locations

Locations

Department of Gastroenterology Tongji Hospital, Tongji Medical college, Huazhong University of Science and technology
RECRUITING

Wuhan, Hubei, 430030, China

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