Does losing your appendix change how gut bugs bounce back after colonoscopy?
NCT ID NCT07478029
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how a common bowel-cleansing drink (PEG) used before colonoscopy changes the gut bacteria in people who have had their appendix removed. Researchers will compare these changes to those in people with an intact appendix. The goal is to understand if the appendix plays a role in helping gut bacteria recover after colonoscopy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Polyethylene glycol (PEG) laxatives
What this could lead to
If successful, this study could reveal whether the appendix helps restore gut bacteria after colonoscopy, and whether its removal affects long-term gut health.
What could go wrong
This is a very small, early-stage observational study with only 10 participants. It does not test a treatment, so results may not lead to direct health changes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Gastroenterology Tongji Hospital, Tongji Medical college, Huazhong University of Science and technology
RECRUITINGWuhan, Hubei, 430030, China
Contact Phone: •••-•••-•••• Email: •••••@•••••