Electric pulses could zap lung tumors without surgery

NCT ID NCT06739031

First seen Aug 21, 2026 ยท Last updated Aug 21, 2026

Summary

This trial is testing whether a device that uses pulsed electric fields (PEF) can safely and effectively destroy early-stage non-small cell lung cancer tumors in people who are not candidates for surgery. The study will measure how completely the tumors are ablated at six months, as well as survival and quality of life. Participants will receive the PEF ablation procedure and be followed for a year to assess outcomes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Pulsed electric field (PEF) ablation device
What this could lead to
If successful, this could offer a new, less invasive treatment option for people with early-stage lung cancer who cannot have surgery, potentially improving local control and survival.
What could go wrong
This is an early-stage trial, so the treatment may not be effective for everyone or may have unexpected side effects. The long-term benefits and risks are not yet known.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine,

    RECRUITING

    Shanghai, China

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