Race to save young livers: can immune drugs stop sudden failure?

NCT ID NCT04862221

Summary

This study is testing if two different immune-suppressing medications can help children survive a sudden, life-threatening liver failure without needing a transplant. About 160 children, aged 1 to 18, will be randomly assigned to receive one of the two drugs or standard supportive care. The goal is to calm an overactive immune response that may be attacking the liver, improving the chance the child's own liver can recover.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Children's Healthcare of Atlanta - Arthur M. Blank Hospital

    WITHDRAWN

    Atlanta, Georgia, 30322, United States

  • Children's Hospital Boston

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Children's Hospital Los Angeles

    RECRUITING

    Los Angeles, California, 90027, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Children's Hospital Vanderbilt

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Children's Hospital of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cleveland Clinic Children's

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Medical Center - Duke Children's

    WITHDRAWN

    Durham, North Carolina, 27710, United States

  • Lucile Packard Children's Hospital

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NYP Morgan Stanley Children's Hospital

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Primary Children's Medical Center

    WITHDRAWN

    Salt Lake City, Utah, 84112, United States

  • Rady Children's Hospital

    RECRUITING

    San Diego, California, 92123, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Riley Hospital for Children

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Louis Children's Hospital

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Children's Mercy Hospital

    RECRUITING

    Kansas City, Missouri, 64108, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Mount Sinai Medical Center

    WITHDRAWN

    New York, New York, 10029, United States

  • UT Southwestern Medical Center Children's Health

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California San Francisco Benioff Children's Hospital

    WITHDRAWN

    San Francisco, California, 94158, United States

  • Yale New Haven Children's Hospital

    WITHDRAWN

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.