New hope for PCOS: drug combo may improve IVF outcomes
NCT ID NCT07604779
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding myoinositol or pioglitazone to metformin improves pregnancy rates in women with PCOS undergoing ICSI (a type of IVF). 150 women will take one of three drug regimens for one month before the procedure. Researchers will track fertilization, pregnancy, and miscarriage rates to find the best approach.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Metformin, myoinositol, and pioglitazone
What this could lead to
If successful, this could identify a better pre-treatment regimen to improve fertilization and pregnancy rates in women with PCOS undergoing ICSI.
What could go wrong
This is a small, early-phase trial with no blinding, so results may not be definitive. Side effects from the drugs are possible, and the study may not lead to a standard treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beni-Suef University Hospital
Banī Suwayf, Beni Suweif Governorate, 62521, Egypt