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New heart scan aims to spot hidden plaque before it strikes

NCT ID NCT07822737

Diagnosis Sponsor: Beijing Chao Yang Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers are testing whether a newer type of CT scan, called photon-counting detector CT, can identify dangerous plaque in heart arteries and predict future heart attacks, chest pain hospitalizations, or heart-related death. The study enrolls 500 adults scheduled for a routine coronary angiogram. Participants receive the CT scan plus standard optical coherence tomography imaging, and researchers track their heart health over time to see if the scan's findings match up with real outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
photon-counting detector CT imaging, a newer type of heart scan
What this could lead to
If it works, doctors could use this scan to flag people at high risk of a heart attack and treat them sooner.
What could go wrong
The study follows people over time and may not prove the scan predicts events better than current tools. It also uses contrast dye and radiation, which carry small risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patient with coronary artery disease

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Scheduled for clinically indicated, non-emergent invasive coronary angiography * Provision of written informed consent and willingness to comply with long-term follow-up Exclusion Criteria: * Estimated glomerular filtration rate \<45 mL/min/1.73 m² * Known allergy to iodinated contrast media * Pregnancy or breastfeeding * Persistent atrial fibrillation or other arrhythmia precluding adequate ECG-gated CT acquisition * Body mass index \>40 kg/m² * Target vessel with a previously implanted stent * Life expectancy \<2 years or any condition that, in the opinion of the investigator, makes follow-up unlikely or participation inappropriate

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Plaque, Amyloid

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery disease Photon-counting computed tomography Plaque

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beijing Chaoyang Hospital，Capital Medical University, Beijing

    RECRUITING

    Beijing, China, 10000, China

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