Cure My Disease

Don't miss your cure!

 Log in / Sign up

Gentler Heart-Lung machine may mean less Post-Surgery inflammation

NCT ID NCT07823400

Knowledge-focused Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers are comparing two ways of running the heart-lung machine during coronary artery bypass surgery to see which triggers less body-wide inflammation. The study follows 80 adults having planned bypass surgery, split by the circulation technique their surgical team uses. Investigators track three routine blood-test ratios before surgery, 6 and 24 hours after, and at discharge, along with selected clinical outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two heart-lung machine techniques used during coronary artery bypass surgery: a minimally invasive system and conventional cardiopulmonary bypass
What this could lead to
If one technique causes less inflammation, it could guide surgeons toward a gentler bypass approach and possibly smoother recoveries.
What could go wrong
This is a small observational study of 80 people, so it can show a link but not prove cause and effect. Blood-test ratios are indirect markers, and results may not apply to emergency or repeat surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients aged 30-70 years undergoing elective coronary artery bypass graft surgery with either minimally invasive extracorporeal circulation or conventional cardiopulmonary bypass at Bursa Yuksek Ihtisas Training and Research Hospital.

Ages

30 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 30-70 years * Patients undergoing elective coronary artery bypass graft surgery * Patients in whom cardiopulmonary bypass is planned * Written informed consent obtained Exclusion Criteria: * Emergency surgery * Redo cardiac surgery * Concomitant valve surgery * Previous open heart surgery * Preoperative renal and/or hepatic failure * Malignancy * Active infection or inflammatory disease-

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Coronary artery disease are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery disease Systemic inflammation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bursa Yuksek Ihtisas Training and Research Hospital

    RECRUITING

    Bursa, Bursa, 16000, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.