Could a vibrating bed help mitochondrial disease patients?

NCT ID NCT05569122

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a special bed that gently moves your legs (passive exercise) can improve how the body uses oxygen in people with mitochondrial disease. Researchers will compare patients to healthy volunteers and also test the bed in children in the ICU. The goal is to understand if passive exercise can help with energy and blood flow, not to cure the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

passive exercise via pGz bed and gentle jogger device

What this could lead to

If successful, this could show that passive exercise improves oxygen use and blood flow in people with mitochondrial disease, pointing toward a non-drug way to manage symptoms.

What could go wrong

This is an early Phase 1 study with only 90 participants, so results may not apply to everyone. The passive exercise devices may not produce meaningful benefits, and the study is mainly measuring effects, not testing a treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

inborn mitochondrial metabolism disorder inborn mitochondrial myopathy mitochondrial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States