Could a vibrating bed help mitochondrial disease patients?
NCT ID NCT05569122
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a special bed that gently moves your legs (passive exercise) can improve how the body uses oxygen in people with mitochondrial disease. Researchers will compare patients to healthy volunteers and also test the bed in children in the ICU. The goal is to understand if passive exercise can help with energy and blood flow, not to cure the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- passive exercise via pGz bed and gentle jogger device
- What this could lead to
- If successful, this could show that passive exercise improves oxygen use and blood flow in people with mitochondrial disease, pointing toward a non-drug way to manage symptoms.
- What could go wrong
- This is an early Phase 1 study with only 90 participants, so results may not apply to everyone. The passive exercise devices may not produce meaningful benefits, and the study is mainly measuring effects, not testing a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MITOCHONDRIAL DISEASES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Worldwide data pool could pave the way for mitochondrial disease trials
- Scientists probe immune cell shifts in ICU patients to unlock sepsis secrets
- Home workouts with video coaching tested for rare muscle disease
- New study tests workplace coaching to keep Parkinson's patients on the job
- Massive genetic study aims to unlock secrets of rare metabolic diseases
- New study seeks to uncover hidden biological clues in kids with autism