New drug cocktail aims to stall pancreatic cancer after chemo
NCT ID NCT06747845
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase II study tests whether a combination of two drugs, niraparib and ipilimumab, can slow tumor growth in people with metastatic pancreatic cancer whose disease has not worsened after platinum-based chemotherapy. About 68 participants will be randomly assigned to receive either the new combo or standard chemotherapy. The main goal is to see how long the cancer stays under control and what side effects occur.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
niraparib and ipilimumab
What this could lead to
If successful, this combination could offer a new maintenance option to delay tumor growth in metastatic pancreatic cancer.
What could go wrong
This is a small phase II trial, so results may not confirm benefit. The combination may cause significant side effects and may not work better than standard chemotherapy.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber Cancer Institute
NOT_YET_RECRUITINGBoston, Massachusetts, 02215, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pennsylvania, Abramson Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact