Tiny study on nerve stimulation for pain halted early

NCT ID NCT03670147

Terminated Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at a type of spinal cord stimulation (SCS) that doesn't cause tingling, called paresthesia-free SCS, in 10 adults with chronic pain. Researchers wanted to see how well it works and how it affects pain perception. The study was terminated early, so the findings are very limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: paresthesia-free spinal cord stimulation (PF-SCS) device programming
What this could lead to: If successful, this could help doctors better select which chronic pain patients will benefit from spinal cord stimulation, an expensive and invasive therapy.
What could go wrong: The study was terminated early with only 10 participants, so results are very limited. It was designed to understand how SCS works, not to prove a new treatment works.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Saethre-Chotzen syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC PAIN SCS

Contacts and locations

Locations

MGH Center for Translational Pain Research

Boston, Massachusetts, 02114, United States

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