Could a simple drug shorten labor? new trial tests papaverine

NCT ID NCT07237880

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a single dose of papaverine, a muscle relaxant, can safely shorten the second stage of labor in pregnant women who had a balloon catheter to start labor. Researchers will compare labor times and outcomes between women who get papaverine and those who get a placebo. The trial aims to find a simple way to reduce labor duration and improve the birth experience.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
papaverine
What this could lead to
If it works, this could offer a simple, safe way to shorten labor for women after cervical ripening, potentially reducing discomfort and complications.
What could go wrong
This is an early-stage trial with only 184 participants. The drug may not shorten labor significantly, and there is a small risk of side effects like allergic reactions or effects on the baby.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hillel Yaffe Medical Center

    RECRUITING

    Hadera, Israel

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