Which labor induction method is safer for moms and babies?

NCT ID NCT07366359

Recruiting now Disease control Sponsor: National Hospital of Obstetrics and Gynecology Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at two common methods to start labor in pregnant women whose water breaks before labor begins (term PROM) and whose cervix is not yet ready. One group gets a vaginal insert (dinoprostone) to soften the cervix, followed by oxytocin if needed. The other group gets oxytocin right away. The goal is to see which method leads to more vaginal births and fewer complications for mother and baby. About 450 women in Hanoi, Vietnam will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dinoprostone (Propess) and Oxytocin
What this could lead to: If this trial succeeds, it could help doctors choose the best way to start labor for women whose water breaks early, potentially leading to more vaginal births and fewer complications.
What could go wrong: This is a single-center study in Vietnam, so results may not apply everywhere. The trial is not blinded, which could introduce bias. Both methods are already used, so no major new risks are expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CERVICAL RIPENING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Fetal Membranes, Premature Rupture preterm premature rupture of the membranes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL RIPENING LABOR, INDUCED PREMATURE RUPTURE OF FETAL MEMBRANES

Contacts and locations

Locations

National Hospital of Obstetrics and Gynecology
RECRUITING

Hanoi, Hanoi, 100000, Vietnam

More trials for these conditions

Other studies related to the condition(s) this trial covers.