Which labor induction method is safer for moms and babies?

NCT ID NCT07366359

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at two common methods to start labor in pregnant women whose water breaks before labor begins (term PROM) and whose cervix is not yet ready. One group gets a vaginal insert (dinoprostone) to soften the cervix, followed by oxytocin if needed. The other group gets oxytocin right away. The goal is to see which method leads to more vaginal births and fewer complications for mother and baby. About 450 women in Hanoi, Vietnam will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dinoprostone (Propess) and Oxytocin

What this could lead to

If this trial succeeds, it could help doctors choose the best way to start labor for women whose water breaks early, potentially leading to more vaginal births and fewer complications.

What could go wrong

This is a single-center study in Vietnam, so results may not apply everywhere. The trial is not blinded, which could introduce bias. Both methods are already used, so no major new risks are expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Fetal Membranes, Premature Rupture preterm premature rupture of the membranes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Hospital of Obstetrics and Gynecology

    RECRUITING

    Hanoi, Hanoi, 100000, Vietnam

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••