Could a simple pill let women start labor at home?

NCT ID NCT05177510

Recruiting now Symptom relief Sponsor: Chelsea and Westminster NHS Foundation Trust Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether a pill called mifepristone can safely and effectively start labor in pregnant women so they can stay home longer instead of being admitted to the hospital right away. About 400 women with a full-term, single baby and an unready cervix will take either mifepristone or a placebo. The goal is to see if more women go into labor within two days, reducing hospital stays and improving the birth experience.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mifepristone
What this could lead to: If it works, this could allow many women to start labor at home instead of in the hospital, making the process shorter and more comfortable.
What could go wrong: This is a mid-stage trial with 400 participants, so results are not yet proven. The drug may not work better than placebo, and there are always risks with any medication during pregnancy.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LABOR, INDUCED

Contacts and locations

Locations

Chelsea and Westminster Hospital
RECRUITING

London, United Kingdom

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