Old drug, new hope: could papaverine soothe chemo nerve damage?
NCT ID NCT07572461
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether papaverine, a drug that relaxes blood vessels, can relieve nerve pain and numbness caused by taxane chemotherapy. About 43 adults whose symptoms haven't improved with standard treatments will receive daily infusions of papaverine for up to three weeks. The goal is to see if it reduces sensory symptoms and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- papaverine hydrochloride injection
- What this could lead to
- If it works, this could offer a new option for people with nerve pain from chemotherapy that hasn't improved with standard treatments.
- What could go wrong
- This is a small, early-phase study with no control group, so results may not be conclusive. It's also not yet recruiting, so outcomes are uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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