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A blood test to spot dangerous pancreatic cysts? scientists are on the hunt

NCT ID NCT07767227

Knowledge-focused Sponsor: Translational Genomics Research Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time

Summary

This study looks at tiny particles called exosomes found in blood and fluid from pancreatic cysts. Researchers want to see if these particles carry unique molecular fingerprints that could help identify cysts that are truly dangerous. About 30 adults scheduled for surgery to remove a pancreatic cyst will provide samples for analysis. The goal is to find clues that might one day lead to better, less invasive ways to decide which cysts need surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test that helps doctors tell which pancreatic cysts are dangerous and need surgery, avoiding unnecessary procedures.
What could go wrong
This is a small pilot study, so findings may not be conclusive. The molecular signatures may not prove reliable in larger, more diverse groups, and the research is exploratory.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2025

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will, primarily, be patients of the clinical Investigators at HOAG and Piedmont Healthcare hospitals who are or will be scheduled for surgical resection of their worrisome pancreatic cyst as part of their clinically indicated care.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Voluntarily agree to participate by giving written informed consent prior to any study-specific procedures. * Subject at least 18 years of age and able to provide consent. Subject is willing and able to comply with requirements of the protocol. * Radiologically documented cyst of the pancreas for which surgical removal is clinically indicated. * Patient will be undergoing a surgical resection of their pancreatic cystic neoplasm. Exclusion Criteria: * Patient who is pregnant at the time of study enrollment and sample collection. * Patient will not be undergoing clinically indicated surgery for a pancreatic cystic neoplasm. * Patient is unwilling or unable to provide informed consent or comply with study procedures.

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Conditions

The condition(s) this trial relates to.

Pancreatic Cyst

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pancreatic cyst

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    2 sites. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Hoag Family Cancer Institute

    RECRUITING

    Newport Beach, California, 92663, United States

    Contact Email: •••••@•••••

  • Piedmont HealthCare

    RECRUITING

    Atlanta, Georgia, 30309, United States

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