New hope for pancreatic cancer? drug combo trial shows promise

NCT ID NCT06119217

Completed Disease control Sponsor: Trishula Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding two experimental drugs (TTX-030 and budigalimab) to standard chemotherapy could help people with metastatic pancreatic cancer live longer without their disease getting worse. 194 adults who had not yet received treatment for their advanced cancer took part. The goal was to see if the new combinations were safe and more effective than chemotherapy alone.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm neoplasm Neoplasm Metastasis pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC CANCER

Contacts and locations

Locations

Investigative SIte

Hot Springs, Arkansas, 71913, United States
Investigative Site

Seoul, 03722, South Korea
Investigative Site

Seoul, 05505, South Korea
Investigative Site

Seoul, 06351, South Korea
Investigative Site

Seoul, 08308, South Korea
Investigative Site

Barcelona, 08009, Spain
Investigative Site

Barcelona, 08035, Spain
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Madrid, 28040, Spain
Investigative Site

Madrid, 28041, Spain
Investigative Site

Madrid, 28050, Spain
Investigative Site

Majadahonda, 28222, Spain
Investigative Site

Pamplona, 31008, Spain
Investigative Site

Valencia, 46009, Spain
Investigative Site

Zaragoza, 50009, Spain
Investigative Site

Kaohsiung City, 833401, Taiwan
Investigative Site

Taichung, 40447, Taiwan
Investigative Site

Tainan, 70403, Taiwan
Investigative Site

Taipei, 112, Taiwan
Investigative Site

Taoyuan, Taiwan
Investigative Site

Tucson, Arizona, 85704, United States
Investigative Site

Bakersfield, California, 93309, United States
Investigative Site

Fullerton, California, 92835, United States
Investigative Site

Los Angeles, California, 90095, United States
Investigative Site

Denver, Colorado, 80218, United States
Investigative Site

St. Petersburg, Florida, 33705, United States
Investigative Site

West Palm Beach, Florida, 33401, United States
Investigative Site

Atlanta, Georgia, 30318, United States
Investigative Site

Wichita, Kansas, 67214, United States
Investigative Site

Baton Rouge, Louisiana, 70809, United States
Investigative Site

Columbia, Maryland, 21044, United States
Investigative Site

Burnsville, Minnesota, 55337, United States
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Las Vegas, Nevada, 89119, United States
Investigative Site

Florham Park, New Jersey, 07932, United States
Investigative Site

Asheville, North Carolina, 28806, United States
Investigative Site

Columbus, Ohio, 43219, United States
Investigative Site

Eugene, Oregon, 97401, United States
Investigative Site

Portland, Oregon, 97239, United States
Investigative Site

Horsham, Pennsylvania, 19044, United States
Investigative Site

Austin, Texas, 78705, United States
Investigative Site

Dallas, Texas, 75246, United States
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San Antonio, Texas, 78258, United States
Investigative Site

Tyler, Texas, 75702, United States
Investigative Site

Arlington, Virginia, 22205, United States
Investigative Site

Norfolk, Virginia, 23502, United States
Investigative Site

Roanoke, Virginia, 24014, United States
Investigative Site

Milwaukee, Wisconsin, 53226, United States
Investigative Site

Albury, New South Wales, 2640, Australia
Investigative Site

Westmead, New South Wales, 2145, Australia
Investigative Site

Herston, Queensland, 4029, Australia
Investigative Site

Besançon, 25030, France
Investigative Site

Dijon, 21079, France
Investigative Site

Lille, 59000, France
Investigative Site

Paris, 75013, France
Investigative Site

Poitiers, 86021, France
Investigative Site

Genova, 16132, Italy
Investigative Site

Meldola, 47014, Italy
Investigative Site

Milan, 20132, Italy
Investigative Site

Pavia, 27100, Italy
Investigative Site

Puglia, 70124, Italy
Investigative Site

Verona, 37134, Italy
Investigative Site

Goyang-si, 10408, South Korea
Investigative Site

Seongam, 13496, South Korea
Investigative Site

Seongnam-si, 13620, South Korea
Investigative Site

Seoul, 03080, South Korea

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