New cocktail of drugs shows promise for tough pancreatic cancer

NCT ID NCT06951997

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing a combination of five drugs (iparomlimab, tuvonralimab, chidamide, nab-paclitaxel, and gemcitabine) as a first treatment for people with metastatic pancreatic cancer. The study aims to see if this mix can shrink tumors and improve survival. It will enroll 33 participants and is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

iparomlimab, tuvonralimab, chidamide, albumin-bound paclitaxel, gemcitabine

What this could lead to

If successful, this could lead to a new first-line treatment option for metastatic pancreatic cancer, potentially improving response rates and survival.

What could go wrong

This is a small, early-phase trial with only 33 participants, so results may not apply to everyone. The drug combination may cause significant side effects and may not prove more effective than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tianjin Medical University Cancer Institute and Hospital

    RECRUITING

    Tianjin, China

    Contact Email: •••••@•••••