New cocktail aims to shrink pancreatic tumors before surgery

NCT ID NCT05984602

First seen Mar 31, 2026 · Last updated Jun 13, 2026 · Updated 14 times

Summary

This early-phase trial tests whether adding two immune-boosting drugs (canakinumab and tislelizumab) to standard chemotherapy can safely shrink pancreatic tumors before surgery. Nine adults with resectable or borderline resectable pancreatic cancer will receive the combination. The main goals are to find the best dose and see how many patients can then have successful surgery.

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Contacts and locations

Locations

  • Ambulatory Care Center

    New York, New York, 10016, United States

  • Clinical Cancer Center

    New York, New York, 10016, United States

  • NYU Langone Ambulatory Care Center East 38th Street

    New York, New York, 10016, United States

Conditions

The condition(s) this trial relates to.

digestive system neoplasm pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.