Could a pill replace needles for acromegaly?
NCT ID NCT04837040
First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times
Summary
This study tests an oral drug called paltusotine for people with acromegaly, a condition where the body makes too much growth hormone. Participants had their disease under control with standard injections and were randomly assigned to receive either paltusotine or a placebo. The main goal was to see if the pill could keep hormone levels normal over 36 weeks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Crinetics Study Site
Los Angeles, California, 90048, United States
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Crinetics Study Site
Torrance, California, 90502, United States
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Crinetics Study Site
Baltimore, Maryland, 21205, United States
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Crinetics Study Site
Boston, Massachusetts, 02114, United States
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Crinetics Study Site
Philadelphia, Pennsylvania, 19104, United States
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Crinetics Study Site
Pittsburgh, Pennsylvania, 15212, United States
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Crinetics Study Site
Nashville, Tennessee, 37203, United States
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Crinetics Study Site
CABA, Buenos Aires, C1012AAR, Argentina
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Crinetics Study Site
Ciudad Autonoma de Buenos Aire, Buenos Aires, C1405BCH, Argentina
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Crinetics Study Site
Córdoba, X5000, Argentina
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Crinetics Study Site
Ghent, 9000, Belgium
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Crinetics Study Site
Fortaleza, Ceará, 60430-275, Brazil
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Crinetics Study Site
Curitiba, Paraná, 80030-110, Brazil
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Crinetics Study Site
Porto Alegre, Rio Grande do Sul, 90410-000, Brazil
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Crinetics Study Site
Rio de Janeiro, 20231-092, Brazil
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Crinetics Study Site
Rio de Janeiro, 21941-913, Brazil
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Crinetics Study Site
Sofia, 1431, Bulgaria
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Crinetics Study Site
Bron, 69677, France
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Crinetics Study Site
Pessac, 33604, France
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Crinetics Study Site
Budapest, 1083, Hungary
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Crinetics Study Site
Pécs, 7624, Hungary
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Crinetics Study Site
Beersheba, 8410101, Israel
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Crinetics Study Site
Petah Tikva, 4941480, Israel
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Crinetics Study Site
Roma, 00168, Italy
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Crinetics Study Site
San Isidro, Lima region, 15023, Peru
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Crinetics Study Site
Bydgoszcz, 85-605, Poland
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Crinetics Study Site
Poznan, 60-355, Poland
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Crinetics Study Site
Kemerovo, Kemerovo Oblast, 650066, Russia
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Crinetics Study Site
Novosibirsk, Novosibirsk Oblast, 630005, Russia
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Crinetics Study Site
Novosibirsk, Novosibirsk Oblast, 630087, Russia
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Crinetics Study Site
Samara, Samara Oblast, 443041, Russia
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Crinetics Study Site
Kazan', Tatarstan Republic, 420097, Russia
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Crinetics Study Site
Moscow, 117186, Russia
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Crinetics Study Site
Moscow, 119435, Russia
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Crinetics Study Site
Moscow, 125008, Russia
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Crinetics Study Site
Belgrade, 11000, Serbia
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Crinetics Study Site
Sheffield, South Yorkshire, S102JF, United Kingdom
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Crinetics Study Site
Coventry, West Midlands, CV2 2DX, United Kingdom
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Crinetics Study Site
London, W12 0HS, United Kingdom
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