Liver Function's impact on drug processing revealed in new study

NCT ID NCT06908954

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 23 times

Summary

This study looked at how moderate and severe liver impairment changes the way the body handles a single dose of the drug palovarotene. Researchers compared 31 participants with liver problems to healthy volunteers. The goal was to understand safety and drug levels in the blood, not to treat any disease.

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Contacts and locations

Locations

  • American Research Corporation/Texas Liver Institute

    San Antonio, Texas, 78215, United States

  • ERG - Clinical Pharmacology of Miami

    Miami, Florida, 33172, United States

  • Orlando Clinical Research Center

    Orlando, Florida, 32809, United States

  • Pinnacle Clinical Research

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.