New combo therapy aims to ease swallowing in incurable esophageal cancer
NCT ID NCT02297217
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial is testing whether adding two chemotherapy drugs (carboplatin and paclitaxel) to standard palliative radiation can better relieve difficulty swallowing in people with incurable esophageal cancer. The study enrolls 50 patients who have trouble swallowing solid foods. The main goal is to see if more patients get lasting improvement in swallowing compared to radiation alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Carboplatin and paclitaxel (chemotherapy drugs) plus external beam radiation
What this could lead to
If it works, this combination could provide better relief from difficulty swallowing and improve quality of life for people with incurable esophageal cancer.
What could go wrong
This is a small, early-phase study with only 50 participants. The added chemotherapy may increase side effects without guaranteeing better symptom relief.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Tom Baker Cancer Centre
RECRUITINGCalgary, Alberta, T2N 4N2, Canada
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••