Which additive makes a nerve block last longer for thyroidectomy pain?

NCT ID NCT05793060

Recruiting now Symptom relief Sponsor: Damanhour Teaching Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding dexmedetomidine or dexamethasone to a standard numbing medicine (bupivacaine) can improve pain control after thyroid removal. Sixty adults undergoing total thyroidectomy will receive one of the two combinations via an ultrasound-guided nerve block. Researchers will track pain scores and side effects for 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexmedetomidine and dexamethasone (added to bupivacaine for a nerve block)
What this could lead to: If one drug works better, it could provide longer-lasting pain relief after thyroid surgery, helping patients recover more comfortably.
What could go wrong: This is a small, early-phase trial with only 60 participants. Results may not apply to everyone, and side effects like slow heart rate or nausea are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANALGESIA

Contacts and locations

Locations

Damanhour Teaching Hospital
RECRUITING

Damanhūr, El-Beheira, Egypt

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