Which additive makes a nerve block last longer for thyroidectomy pain?
NCT ID NCT05793060
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding dexmedetomidine or dexamethasone to a standard numbing medicine (bupivacaine) can improve pain control after thyroid removal. Sixty adults undergoing total thyroidectomy will receive one of the two combinations via an ultrasound-guided nerve block. Researchers will track pain scores and side effects for 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexmedetomidine and dexamethasone (added to bupivacaine for a nerve block)
What this could lead to
If one drug works better, it could provide longer-lasting pain relief after thyroid surgery, helping patients recover more comfortably.
What could go wrong
This is a small, early-phase trial with only 60 participants. Results may not apply to everyone, and side effects like slow heart rate or nausea are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Damanhour Teaching Hospital
RECRUITINGDamanhūr, El-Beheira, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••