New study aims to cut opioid use after joint replacement
NCT ID NCT06230081
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding ultrasound-guided nerve blocks before hip or knee replacement surgery can reduce pain and opioid use compared to standard pain management. 400 adults with osteoarthritis will be enrolled. The goal is to improve recovery and reduce side effects like nausea.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ropivacaine and clonidine (local anesthetic and pain reliever)
- What this could lead to
- If successful, this could lead to better pain control and faster recovery after joint replacement, with less reliance on opioids.
- What could go wrong
- This is a single study with 400 participants, and results may not apply to all patients. Nerve blocks carry small risks like infection or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dept of Anaesthesiology, Trelleborg Hospital
Trelleborg, Sweden
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