New study aims to cut opioid use after joint replacement
NCT ID NCT06230081
First seen May 12, 2026 · Last updated Jun 24, 2026 · Updated 7 times
Summary
This study tests whether adding ultrasound-guided nerve blocks before hip or knee replacement surgery can reduce pain and opioid use compared to standard pain management. 400 adults with osteoarthritis will be enrolled. The goal is to improve recovery and reduce side effects like nausea.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dept of Anaesthesiology, Trelleborg Hospital
Trelleborg, Sweden
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ropivacaine and clonidine (local anesthetic and pain reliever)
What this could lead to
If successful, this could lead to better pain control and faster recovery after joint replacement, with less reliance on opioids.
What could go wrong
This is a single study with 400 participants, and results may not apply to all patients. Nerve blocks carry small risks like infection or nerve damage.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.