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Can learning about pain make exercise work better for period cramps?

NCT ID NCT07817628

Symptom relief Sponsor: Harran University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
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First seen Sep 14, 2026 · Last updated Sep 17, 2026 · Updated 3 times

Summary

Researchers are testing whether adding pain neuroscience education to a six-week exercise program helps women with primary dysmenorrhea, the recurring menstrual pain that is not caused by another condition. Sixty-two women aged 18 to 35 join the trial and are split into two groups. Both groups do the same exercise program three times a week, while one group also attends weekly sessions about how pain works in the body. The trial measures menstrual pain intensity, daily activity interference, painkiller use, and how the nervous system processes pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Pain neuroscience education plus a standardized exercise program
What this could lead to
If it works, this could offer women a non-drug way to manage period pain by combining exercise with education about how pain works.
What could go wrong
The trial is small and early, so results may not hold for all women or last beyond a few months. Exercise and education carry little risk, but they may not relieve pain better than exercise alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

62 people

The number who actually took part.

Started

Jul 2025

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged 18-35 years * Menstrual cycles of 21-35 days * Symptoms consistent with primary dysmenorrhea for at least 6 months * At least 2 years since menarche * Recurrent menstrual pain during at least 2 menstrual cycles * Menstrual pain intensity of at least 4/10 on the Numerical Rating Scale during menstruation * Willingness to participate * Provision of written informed consent Exclusion Criteria: * Endometriosis, adenomyosis, pelvic inflammatory disease, uterine fibroids, or another gynecological pathology capable of explaining menstrual pain * Use of hormonal contraceptives or other hormonal treatment * Regular analgesic or antidepressant use * Severe orthopedic, neurological, gynecological, chronic, or systemic disease * Any health condition preventing participation in the exercise program * Previous structured pain neuroscience education * Pregnancy or lactation * Menstrual irregularity outside the predefined cycle criteria * Failure to meet the predefined menstrual pain-severity criterion

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Conditions

The condition(s) this trial relates to.

Dysmenorrhea Motor Activity primary dysmenorrhea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Primary dysmenorrhea

Contacts and locations

Locations

  • Harran University Faculty of Medicine Training and Research Hospital

    Sanliurfa, Şanlıurfa, 63000, Turkey (Türkiye)

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