Could a faster pacemaker setting help heart amyloidosis patients feel better?
NCT ID NCT07413081
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether increasing the pacemaker's lower rate from 60 to 80 beats per minute improves quality of life and daily function in people with ATTR cardiac amyloidosis. The heart in this condition is stiff and depends on a faster heart rate to pump blood. Thirty-four participants will try both settings in a crossover design to see which works better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pacemaker rate adjustment
What this could lead to
If it works, this could point toward a simple way to improve daily function and well-being for people with cardiac amyloidosis who have a pacemaker.
What could go wrong
This is a small, early-stage trial with only 34 participants, so results may not apply to everyone. The benefit seen in similar conditions may not hold true for amyloidosis.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Locations
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Aarhus University Hospital
Aarhus, Denmark
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Academic University Hospital
Uppsala, Sweden
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Karolinska University Hospital
Stockholm, Sweden
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Linköping University Hospital
Linköping, Sweden
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Norrland University Hospital
Umeå, Sweden
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Rigshospitalet
Copenhagen, Denmark
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Sahlgrenska University Hospital
Gothenburg, Sweden
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Skane University Hospital
Lund, Sweden
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Skellefteå Hospital
Skellefteå, Sweden
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