Scientists deliberately infect volunteers with malaria to study the disease

NCT ID NCT04083508

First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This study aims to see if it's safe and possible to give healthy Thai adults a controlled infection of P. vivax malaria through mosquito bites. Six volunteers will be infected and monitored closely. The goal is to develop a reliable model for future research on malaria and immune responses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Mosquito bites infected with P. vivax malaria
What this could lead to
If successful, this could create a reliable model to study P. vivax malaria and test future treatments or vaccines.
What could go wrong
This is a very early, tiny study (6 people) focused on feasibility, not treatment. It may not lead to any direct benefit for participants or patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Tropical Medicine

    Bangkok, 10400, Thailand

More trials for these conditions

Other studies related to the condition(s) this trial covers.