Scientists bite back: testing malaria infection with live mosquitoes
NCT ID NCT07257965
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aims to find the smallest number of infected mosquito bites needed to give healthy adults malaria. Twenty-four volunteers will be bitten by 1, 2, or 3 mosquitoes carrying the Plasmodium vivax parasite. The results will help researchers develop better ways to test future malaria vaccines in real-world settings.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Mosquito bite with Plasmodium vivax parasites
- What this could lead to
- If successful, this could create a safer and more accurate way to test malaria vaccines in people who are most at risk.
- What could go wrong
- This is a very early study with only 24 healthy adults, so results may not apply to everyone. Participants will be intentionally infected with malaria, which carries risks like fever and illness.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Tropical Medicine, Mahidol University
RECRUITINGBangkok, 10400, Thailand
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