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Could ozone gas make dental implants stronger?

NCT ID NCT07687680

Disease control Sponsor: Zeliha Başak Çakır Erdil Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 21, 2026 · Updated 3 times

Summary

This study tests whether using ozone gas to disinfect the implant site before placing a dental implant leads to better stability compared to standard disinfection methods. Healthy adults who need at least two dental implants will receive ozone at one site and standard care at the other. Implant stability is measured right after placement and again three months later to see if ozone makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ozone gas
What this could lead to
If ozone disinfection improves implant stability, it could lead to better success rates for dental implants and faster healing.
What could go wrong
This is a small, early-stage trial with only 51 participants. Ozone may not provide any benefit over standard disinfection, and there could be unknown risks from ozone exposure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

51 people

The number who actually took part.

Started

Nov 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Systemically healthy individuals requiring at least two dental implants. * Presence of symmetrical or contralateral edentulous sites suitable for dental implant placement. * Adequate bone volume for implant placement without the need for simultaneous bone augmentation. * Ability and willingness to provide written informed consent and comply with the study protocol. Exclusion Criteria: * Adults aged 18 years or older. * Systemically healthy individuals requiring at least two dental implants. * Presence of symmetrical or contralateral edentulous sites suitable for dental implant placement. * Adequate bone volume for implant placement without the need for simultaneous bone augmentation. * Ability and willingness to provide written informed consent and comply with the study protocol.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental implant placement Ozone therapy

Contacts and locations

Locations

  • Faculty of Dentistry, Adıyaman University

    Adıyaman, Merkez, 02030, Turkey (Türkiye)

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