Ozone treatment tested to boost heart function in failure patients

NCT ID NCT07134972

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial tested whether ozone therapy can help people with heart failure and reduced ejection fraction. Sixty participants received ozone infusions twice a week for two months. Researchers measured coronary flow reserve, exercise capacity, and heart function before and after treatment. The goal was to see if ozone could improve blood flow and reduce heart failure episodes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ozone therapy (ozonized blood infusion)

What this could lead to

If it works, this could point toward a complementary therapy to improve blood flow and exercise ability in heart failure patients.

What could go wrong

This is a small, completed trial with only 60 participants, so results may not apply widely. Ozone therapy is experimental and not a standard heart failure treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medicana International Hospital Istanbul

    Istanbul, Turkey (Türkiye)