Ozone treatment tested to boost heart function in failure patients

NCT ID NCT07134972

Completed Disease control Sponsor: Ekrem Bilal Karaayvaz Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial tested whether ozone therapy can help people with heart failure and reduced ejection fraction. Sixty participants received ozone infusions twice a week for two months. Researchers measured coronary flow reserve, exercise capacity, and heart function before and after treatment. The goal was to see if ozone could improve blood flow and reduce heart failure episodes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ozone therapy (ozonized blood infusion)
What this could lead to: If it works, this could point toward a complementary therapy to improve blood flow and exercise ability in heart failure patients.
What could go wrong: This is a small, completed trial with only 60 participants, so results may not apply widely. Ozone therapy is experimental and not a standard heart failure treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEART FAILURE AND REDUCED EJECTION FRACTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE AND REDUCED EJECTION FRACTION

Contacts and locations

Locations

Medicana International Hospital Istanbul

Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.