Could ozone gas be the secret to faster gum healing?

NCT ID NCT07517328

Completed Symptom relief Sponsor: Ataturk University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether applying ozone gas to surgical wounds in the mouth can help gums heal faster after gum surgery. Twenty-four people with enlarged gums due to chronic inflammation took part. Each person had two similar areas treated: one with standard surgery alone, and the other with surgery plus ozone gas applied for one minute per tooth. Researchers checked healing using cell samples and gum health measurements over three weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: gaseous ozone
What this could lead to: If it works, this could offer a simple, low-cost way to speed up gum healing after surgery and reduce discomfort.
What could go wrong: This is a small, early-stage study with only 24 participants. The results may not apply to everyone, and ozone therapy is not yet a standard treatment.

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Conditions

The condition(s) this trial relates to.

Gingival Hyperplasia gingival overgrowth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC INFLAMMATORY GINGIVAL ENLARGEMENT GINGIVAL ENLARGEMENT GINGIVAL HYPERPLASIA

Contacts and locations

Locations

Ataturk University Faculty of Dentistry, Department of Periodontology

Erzurum, Turkey (Türkiye)

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