Love hormone may curb opioid addiction risk in seniors
NCT ID NCT05761860
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase study tests whether giving oxytocin (a nasal spray) alongside oxycodone can reduce the drug's abuse potential while still easing pain. Researchers will measure pain response, subjective effects, and decision-making in 45 healthy older adults over six lab sessions. The goal is to see if oxytocin can make opioids safer without losing their painkilling power.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oxytocin nasal spray
What this could lead to
If it works, this could point toward a way to make opioid painkillers safer and less addictive for older adults.
What could go wrong
This is a very early, small lab study (45 people) in healthy older adults without chronic pain. Results may not apply to real-world pain patients, and the combination's safety and effectiveness are far from proven.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Florida
RECRUITINGGainesville, Florida, 32611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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