Oxygen debate: lower levels may be safer for COPD patients
NCT ID NCT04223050
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study aimed to find the best oxygen level for people hospitalized with a sudden worsening of COPD. It compared giving enough oxygen to reach 88-92% saturation versus over 94%. The trial was stopped early after only 23 people took part, so the results are not strong enough to change practice.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oxygen gas
What this could lead to
If successful, this could clarify the safest oxygen level for COPD patients during a flare-up, potentially reducing deaths.
What could go wrong
The trial was terminated early with only 23 participants, so results are very limited and may not be reliable. It is unclear if either oxygen target is truly better.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Holbæk Sygehus
Holbæk, 4300, Denmark
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Odense University Hospital
Odense, 5000, Denmark
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Sydvestjysk Sygehus
Esbjerg, 6700, Denmark
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Sygehus Lillebælt, Kolding
Kolding, 6000, Denmark