Frozen ovary transplant could help cancer survivors have babies

NCT ID NCT01870752

Recruiting now Disease control Sponsor: Abramson Cancer Center at Penn Medicine Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether transplanting a woman's own frozen ovarian tissue can restore fertility after cancer treatment. Ten women who became infertile due to chemotherapy or radiation will receive the transplant. The goal is to see if they can get pregnant and have normal menstrual cycles again.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transplant of previously frozen ovarian tissue
What this could lead to: If it works, this could offer a way for women to have biological children after cancer treatments that damaged their ovaries.
What could go wrong: This is a very small early study (10 people) and may not lead to a widely available treatment. Risks include surgical complications and possible cancer recurrence.

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Conditions

The condition(s) this trial relates to.

infertility disorder ovarian dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFERTILE FEMALES OR FEMALES WITH OVARIAN INSUFFICIENCY

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Abramson Cancer Center of the University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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