Ovarian tissue moved to thigh may prevent early menopause in cervical cancer patients
NCT ID NCT05462379
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 39 times
Summary
This study tests whether moving a piece of ovary to the fatty tissue of the inner thigh before pelvic radiation can keep it working. Twenty-two women aged 35 or younger with advanced cervical cancer will take part. The goal is to see if the graft produces hormones normally, potentially avoiding early menopause without needing hormone replacement therapy.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Instituto do Cancer do Estado de São Paulo
São Paulo, 01246-000, Brazil
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ovarian tissue graft
What this could lead to
If it works, this could offer a way for young women with cervical cancer to keep their natural hormone production after pelvic radiation, avoiding early menopause.
What could go wrong
This is an early phase 1-2 trial with only 22 participants, so results may not apply to everyone. The graft may not work or could cause complications.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.