Scientists test 'Vaccine' to train immune system to fight ovarian cancer

NCT ID NCT03029403

Summary

This study is testing whether a three-drug combination can help the body's immune system fight advanced ovarian, fallopian tube, or primary peritoneal cancer that has returned after initial treatment. The treatment includes an immunotherapy drug (pembrolizumab), an investigational cancer vaccine (DPX-Survivac), and a low-dose chemotherapy pill (cyclophosphamide). The goal is to see if this combination can shrink tumors and control the disease in 47 patients who have already had standard platinum-based chemotherapy.

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Contacts and locations

Locations

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.