New drug combo tested in fight against returning bone cancer
NCT ID NCT03628209
Summary
This study is testing whether two immunotherapy drugs, nivolumab alone or combined with azacitidine, are safe and can help prevent cancer from coming back in patients with recurrent osteosarcoma (a type of bone cancer) that has spread to the lungs but can be surgically removed. Participants receive the drugs before and after surgery to remove the lung tumors. The main goal is to find a safe dose and see if this approach keeps patients cancer-free one year after surgery.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OSTEOSARCOMA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Alfred I DuPont Hospital for Children
Wilmington, Delaware, 19803, United States
-
Carolina Medical Center, Levine Cancer Institute
Charlotte, North Carolina, 28203, United States
-
Children's Hospital of Colorado
Aurora, Colorado, 80045, United States
-
Children's Hospital of Los Angeles, USC Norris Comprehensive Cancer Center
Los Angeles, California, 90027, United States
-
Cleveland Clinic
Cleveland, Ohio, 44195, United States
-
Connecticut Children's Medical Center
Hartford, Connecticut, 06106, United States
-
Duke Health
Durham, North Carolina, 27708, United States
-
H. Lee Moffitt Cancer Center and Research Institute, Coordinating Center
Tampa, Florida, 33612, United States
-
Johns Hopkins All Children's Hospital
St. Petersburg, Florida, 33701, United States
-
Johns Hopkins University, Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
-
Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
-
Nemours Children's Clinic
Orlando, Florida, 32806, United States
-
Nemours Children's Hospital
Jacksonville, Florida, 32207, United States
-
Roswell Park Comprehensive Cancer Center
Buffalo, New York, 14203, United States
-
Shand's Hospital for Children at the University of Florida
Gainesville, Florida, 32610, United States
-
University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
-
University of Kentucky, Markey Cancer Center
Lexington, Kentucky, 40536, United States
-
University of Miami - Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
-
University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
-
University of Texas M.D. Anderson Cancer Center
Houston, Texas, 77030, United States
-
University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
-
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, 37232, United States
Conditions
Explore the condition pages connected to this study.