Moldable bone putty could improve spine surgery outcomes

NCT ID NCT04775537

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a moldable bone graft material called OssiMend Bioactive Moldable in people having lumbar spine fusion surgery for degenerative disc disease. The goal is to see if it helps the bones fuse together successfully and reduces pain and disability. About 120 adults who have not improved with other treatments will be enrolled and followed for 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

OssiMend Bioactive Moldable (a moldable bone graft material used during spine surgery)

What this could lead to

If successful, this could provide a better option for spinal fusion, potentially improving bone healing and reducing pain for people with degenerative disc disease.

What could go wrong

This is a relatively small study (120 people) and results may not apply to everyone. The device is already used, but this trial is testing it in a specific surgical context, so benefits may be modest or not seen at all.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder vertebral column disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hartford Hospital

    RECRUITING

    Hartford, Connecticut, 06102, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • McKenzie-willamette Medical Center

    COMPLETED

    Eugene, Oregon, 97401, United States

  • San Diego Neurosurgery

    NOT_YET_RECRUITING

    Encinitas, California, 92024, United States

    Contact

    Contact

  • University Orthopaedic Associates, Division of OrthoNJ

    NOT_YET_RECRUITING

    Somerset, New Jersey, 08873, United States

    Contact

    Contact Email: •••••@•••••