Moldable bone putty could improve spine surgery outcomes

NCT ID NCT04775537

Recruiting now Disease control Sponsor: Collagen Matrix Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a moldable bone graft material called OssiMend Bioactive Moldable in people having lumbar spine fusion surgery for degenerative disc disease. The goal is to see if it helps the bones fuse together successfully and reduces pain and disability. About 120 adults who have not improved with other treatments will be enrolled and followed for 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: OssiMend Bioactive Moldable (a moldable bone graft material used during spine surgery)
What this could lead to: If successful, this could provide a better option for spinal fusion, potentially improving bone healing and reducing pain for people with degenerative disc disease.
What could go wrong: This is a relatively small study (120 people) and results may not apply to everyone. The device is already used, but this trial is testing it in a specific surgical context, so benefits may be modest or not seen at all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder vertebral column disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEGENERATIVE DISC DISEASE SPINAL DISEASE

Contacts and locations

Locations

Hartford Hospital
RECRUITING

Hartford, Connecticut, 06102, United States
McKenzie-willamette Medical Center
COMPLETED

Eugene, Oregon, 97401, United States
San Diego Neurosurgery
NOT_YET_RECRUITING

Encinitas, California, 92024, United States
University Orthopaedic Associates, Division of OrthoNJ
NOT_YET_RECRUITING

Somerset, New Jersey, 08873, United States

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