New drug combo aims to stall lung cancer progression

NCT ID NCT03909334

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 22 times

Summary

This study tests whether adding ramucirumab to the standard drug osimertinib can delay cancer growth in people with advanced EGFR-mutant non-small cell lung cancer. About 160 participants who have not had prior targeted therapy will be randomly assigned to receive either the combination or osimertinib alone. The main goal is to see how long the cancer stays under control.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

  • Fred Hutchinson Cancer Research Center

    Seattle, Washington, 98109, United States

  • Georgetown University

    Washington D.C., District of Columbia, 20057, United States

  • Indiana Univesity Melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, 46202, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • New York University Cancer Center

    New York, New York, 10016, United States

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, 60611, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Summit Medical Group, PA

    Berkeley Heights, New Jersey, 07922, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.